Article
The -463G/A and -129G/A myeloperoxidase-encoding gene polymorphism in chronic obstructive pulmonary disease.
Advances in respiratory medicine - 1 Jan 2020
Witusik Andrzej, Mokros Łukasz, Szemraj Janusz, Kuna Piotr, Pietras Tadeusz
Abstract excerpt
INTRODUCTION: Neutrophils are involved in the pathogenesis of chronic obstructive pulmonary disease (COPD). Myeloperoxidase is an important bactericidal granulocytic enzyme. It is of interest to question whether or not the polymorphic variants of the myeloperoxidase-encoding gene are associated with the risk of developing COPD. MATERIAL AND METHODS: The study determined the risk of COPD development in 186 COPD...
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