Article
Genetic variation of myeloperoxidase gene contributes to atopic asthma susceptibility: a preliminary association study in Russian population.
The Journal of asthma : official journal of the Association for the Care of Asthma - 1 Jun 2009
Polonikov A V, Solodilova M A, Ivanov V P
Abstract excerpt
BACKGROUND: Recently, we have shown that both antioxidant and oxidant genes are proper candidates for asthma susceptibility genes. OBJECTIVES: In the present study we investigated whether a common polymorphism -463G > A in the promoter of myeloperoxidase (MPO) gene, an enzyme producing hypohalogenic oxidants, is associated with the risk of bronchial asthma. METHODS: We studied 429 unrelated Russian subjects...
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