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Article

Nuclear-encoded mitochondrial ribosomal proteins are required to initiate gastrulation.

Development (Cambridge, England) - 26 May 2020

Cheong Agnes, Archambault Danielle, Degani Rinat, Iverson Elizabeth, Tremblay Kimberly D, Mager Jesse

Abstract excerpt

Mitochondria are essential for energy production and although they have their own genome, many nuclear-encoded mitochondrial ribosomal proteins (MRPs) are required for proper function of the organelle. Although mutations in MRPs have been associated with human diseases, little is known about their role during development. Presented here are the null phenotypes for 21 nuclear-encoded mitochondrial proteins and...

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Identifiers

PMID: 32376682
DOI: 10.1242/dev.188714
PMCID: PMC7272334

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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