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Article

DIP-microhaplotypes: new markers for detection of unbalanced DNA mixtures.

International journal of legal medicine - 1 Jan 2021

Liu Jinding, Hao Ting, Cheng Xiaojuan, Wang Jiaqi, Li Wenyan, Liu Zidong, Shi Jie, Li Zeqin, Ren Jianbo, Yun Keming, Zhang Gengqian

Abstract excerpt

The identification of a suspect in a degraded and unbalanced DNA mixture has been a challenge for the standard short tandem repeat polymorphisms (STR) typing. Several methods have been introduced to solve this problem, such as DIP-STR, DIP-SNP, and SNP-STR markers. In this study, we proposed DIP-microhaplotype (deletion/insertion linked a chain of SNPs) as a kind of new genetic marker to type the unbalanced and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32372232
DOI: 10.1007/s00414-020-02288-y

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