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Article

DIP-STR: highly sensitive markers for the analysis of unbalanced genomic mixtures.

Human mutation - 1 Apr 2013

Castella Vincent, Gervaix Joëlle, Hall Diana

Abstract excerpt

Samples containing highly unbalanced DNA mixtures from two individuals commonly occur both in forensic mixed stains and in peripheral blood DNA microchimerism induced by pregnancy or following organ transplant. Because of PCR amplification bias, the genetic identification of a DNA that contributes trace amounts to a mixed sample represents a tremendous challenge. This means that standard genetic markers, namely...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23355272
DOI: 10.1002/humu.22280
PMCID: PMC3675636

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