Article
A set of 14 DIP-SNP markers to detect unbalanced DNA mixtures.
Biochemical and biophysical research communications - 4 Mar 2018
Liu Zhizhen, Liu Jinding, Wang Jiaqi, Chen Deqing, Liu Zidong, Shi Jie, Li Zeqin, Li Wenyan, Zhang Gengqian, Du Bing
Abstract excerpt
Unbalanced DNA mixture is still a difficult problem for forensic practice. DIP-STRs are useful markers for detection of minor DNA but they are not widespread in the human genome and having long amplicons. In this study, we proposed a novel type of genetic marker, termed DIP-SNP. DIP-SNP refers to the combination of INDEL and SNP in less than 300bp length of human genome. The multiplex PCR and SNaPshot assay were...
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