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Tumor specific methylome in Chinese high-grade serous ovarian cancer characterized by gene expression profile and tumor genotype.

Gynecologic oncology - 1 Jul 2020

Song Fangfang, Li Lian, Zhang Baifeng, Zhao Yanrui, Zheng Hong, Yang Meng, Li Xiangchun, Tian Jing, Huang Caiyun, Liu Luyang, Wang Qinghua, Zhang Wei, Chen Kexin

Abstract excerpt

OBJECTIVE: Extensive genetic and limited epigenetics have been characterized by the Cancer Genome Atlas (TCGA) among Western High-grade serous ovarian cancer (HGSOC). The present study aimed to characterize Chinese HGSOC at genome scale. METHODS: We used reduced representation bisulfite sequencing to investigate whole-genome and tumor-specific DNA methylation in 21 HGSOC tumors paired with their normal tissues,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 32362568
DOI: 10.1016/j.ygyno.2020.04.688

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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