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Article

COVID-19 and nicotine as a mediator of ACE-2

29 Apr 2020

Abstract excerpt

We recently reported that current smokers and those with COPD had higher airway epithelial cell expression of the angiotensin-converting enzyme II (ACE-2) viral entry receptor [1]. We thus read with great interest the work of P. Russo and co-workers, which proposes a mechanism for this finding, namely that this upregulation is mediated by nicotine exposure specifically through the α7 subtype of nicotine...

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Identifiers

PMID: 32350104
DOI: 10.1183/13993003.01261-2020

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