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Article

Human NANOS1 Represses Apoptosis by Downregulating Pro-Apoptotic Genes in the Male Germ Cell Line.

International journal of molecular sciences - 24 Apr 2020

Janecki Damian M, Ilaslan Erkut, Smialek Maciej J, Sajek Marcin P, Kotecki Maciej, Ginter-Matuszewska Barbara, Krainski Patryk, Jaruzelska Jadwiga, Kusz-Zamelczyk Kamila

Abstract excerpt

While two mouse NANOS paralogues, NANOS2 and NANOS3, are crucial for maintenance of germ cells by suppression of apoptosis, the mouse NANOS1 paralogue does not seem to regulate these processes. Previously, we described a human NANOS1 p.[(Pro34Thr);(Ser83del)] mutation associated with the absence of germ cells in seminiferous tubules of infertile patients, which might suggest an anti-apoptotic role of human...

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Identifiers

PMID: 32344590
DOI: 10.3390/ijms21083009
PMCID: PMC7215683

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Human NANOS1 Represses Apoptosis by Downregulating Pro-Apoptotic Genes in the Male Germ Cell Line.PMID 32344590Read ↗

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