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Article

MicroRNA-34c Enhances Murine Male Germ Cell Apoptosis through Targeting ATF1

30 Mar 2012

Abstract excerpt

BACKGROUND: MicroRNAs (miRNAs) play vital regulatory roles in many cellular processes. The expression of miRNA (miR)-34c is highly enriched in adult mouse testis, but its roles and underlying mechanisms of action are not well understood. METHODOLOGY/PRINCIPAL FINDINGS: In the present study, we show that miR-34c is detected in mouse pachytene spermatocytes and continues to be highly expressed in spermatids. To...

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PMID: 22479460
DOI: 10.1371/journal.pone.0033861

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