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Mutations Upstream of the TBX5 and PITX1 Transcription Factor Genes Are Associated with Feathered Legs in the Domestic Chicken.

Molecular biology and evolution - 1 Sept 2020

Li Jingyi, Lee MiOk, Davis Brian W, Lamichhaney Sangeet, Dorshorst Ben J, Siegel Paul B, Andersson Leif

Abstract excerpt

Feathered leg is a trait in domestic chickens that has undergone intense selection by fancy breeders. Previous studies have shown that two major loci controlling feathered leg are located on chromosomes 13 and 15. Here, we present genetic evidence for the identification of candidate causal mutations at these loci. This was accomplished by combining classical linkage mapping using an experimental cross segregating...

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Identifiers

PMID: 32344431
DOI: 10.1093/molbev/msaa093
PMCID: PMC7475036

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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