Article
Expanding the Spectrum of EWSR1-NFATC2-rearranged Benign Tumors: A Common Genomic Abnormality in Vascular Malformation/Hemangioma and Simple Bone Cyst.
The American journal of surgical pathology - 1 Dec 2021
Ong Sheena L M, Lam Suk Wai, van den Akker Brendy E W M, Kroon Herman M, Briaire-de Bruijn Inge H, Cleven Arjen H G, Savci-Heijink Dilara C, Cleton-Jansen Anne-Marie, Baumhoer Daniel, Szuhai Karoly, Bovée Judith V M G
Abstract excerpt
A simple bone cyst (SBC) is a cystic bone lesion predominantly affecting young males. The cyst is lined by a fibrous membrane and filled with serosanguinous fluid. EWSR1/FUS-NFATC2 rearrangements were recently identified in SBC. We here report exactly the same rearrangement in 3 lesions diagnosed as vascular malformations of 2 elderly patients. In total, through Archer FusionPlex, fluorescence in situ...
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