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Article

Genetically Determined Birthweight Associates With Atrial Fibrillation: A Mendelian Randomization Study.

Circulation. Genomic and precision medicine - 1 Jun 2020

Kember Rachel L, Levin Michael G, Cousminer Diana L, Tsao Noah, Judy Renae, Schur Gayatri M, Lubitz Steven A, Ellinor Patrick T, McCormack Shana E, Grant Struan F A, Rader Daniel J, Voight Benjamin F, Damrauer Scott M

Abstract excerpt

BACKGROUND: Atrial fibrillation is a common cardiovascular disorder, characterized by irregular electrical activity in the upper chambers of the heart. Both chronic cardiometabolic risk factors and genetics have been shown to contribute to the development of atrial fibrillation. Birthweight has also been associated with risk of atrial fibrillation. METHODS: In the current study, we utilized a genetic approach to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32340472
DOI: 10.1161/CIRCGEN.119.002553
PMCID: PMC7299774

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