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Article

Effects of Vitamin D Receptor, Metallothionein 1A, and 2A Gene Polymorphisms on Toxicity of the Peripheral Nervous System in Chronically Lead-Exposed Workers.

International journal of environmental research and public health - 23 Apr 2020

Liu Hsin-Liang, Chuang Hung-Yi, Hsu Chien-Ning, Lee Su-Shin, Yang Chen-Cheng, Liu Kuan-Ting

Abstract excerpt

Chronic exposure to lead is neurotoxic to the human peripheral sensory system. Variant vitamin D receptor (VDR) genes and polymorphisms of metallothioneins (MTs) are associated with different outcomes following lead toxicity. However, no evidence of a relationship between lead neurotoxicity and polymorphisms has previously been presented. In this study, we investigated the relationship between the polymorphisms...

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Identifiers

PMID: 32340109
DOI: 10.3390/ijerph17082909
PMCID: PMC7215364

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