Article
Pre-transplant FLT3/ITD status predicts outcome in FLT3-mutated acute myeloid leukemia following allogeneic stem cell transplantation.
Annals of hematology - 1 Aug 2020
Helbig Grzegorz, Koclęga Anna, Wieczorkiewicz-Kabut Agata, Woźniczka Krzysztof, Kopińska Anna, Boral Kinga, Grygoruk-Wiśniowska Iwona, Stachowicz Małgorzata, Karolczyk Agnieszka
Abstract excerpt
Acute myeloid leukemia (AML) with fetal liver tyrosine kinase 3 (FLT3) internal tandem duplication (ITD) is associated with poor prognosis, and allogeneic stem cell transplantation (Allo-SCT) seems to be the preferred therapeutic approach. However, the predictors of post-transplant outcomes were not well-defined. The aim of the study was to evaluate the significance of FLT3/ITD mutation by polymerase chain...
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