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Article

Silencing of lncRNA XIST suppresses proliferation and autophagy and enhances vincristine sensitivity in retinoblastoma cells by sponging miR-204-5p.

1 Apr 2020

Abstract excerpt

OBJECTIVE: Retinoblastoma (RB) is the most prevalent intraocular malignancy in childhood. Long non-coding RNAs (lncRNAs) have been found as critical oncogenic drivers and tumor suppressor in RB. The aim of the present work was to investigate the impact and mechanism of XIST on RB cell autophagy and vincristine (VCR) sensitivity. MATERIALS AND METHODS: The levels of XIST and miR-204-5p were assessed by...

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Identifiers

PMID: 32329826
DOI: 10.26355/eurrev_202004_20812

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