Article
miRNAs as potential game-changers in retinoblastoma: Future clinical and medicinal uses.
Pathology, research and practice - 1 Jul 2023
Doghish Ahmed S, Moustafa Hebatallah Ahmed Mohamed, Elballal Mohammed S, Sarhan Omnia M, Darwish Samar F, Elkalla Wagiha S, Mohammed Osama A, Atta Asmaa M, Abdelmaksoud Nourhan M, El-Mahdy Hesham A, Ismail Ahmed, Abdel Mageed Sherif S, Elrebehy Mahmoud A, Abdelfatah Amr M, Abulsoud Ahmed I
Abstract excerpt
Retinoblastoma (RB) is a rare tumor in children, but it is the most common primitive intraocular malignancy in childhood age, especially those below three years old. The RB gene (RB1) undergoes mutations in individuals with RB. Although mortality rates remain high in developing countries, the survival rate for this type of cancer is greater than 95-98% in industrialized countries. However, it is lethal if left...
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