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Article

Role of Genetic Variations in the Hepatic Handling of Drugs.

International journal of molecular sciences - 20 Apr 2020

Marin Jose J G, Serrano Maria A, Monte Maria J, Sanchez-Martin Anabel, Temprano Alvaro G, Briz Oscar, Romero Marta R

Abstract excerpt

The liver plays a pivotal role in drug handling due to its contribution to the processes of detoxification (phases 0 to 3). In addition, the liver is also an essential organ for the mechanism of action of many families of drugs, such as cholesterol-lowering, antidiabetic, antiviral, anticoagulant, and anticancer agents. Accordingly, the presence of genetic variants affecting a high number of genes expressed in...

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Identifiers

PMID: 32326111
DOI: 10.3390/ijms21082884
PMCID: PMC7215464

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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