Article
Interaction between Mas1 and AT1RA contributes to enhancement of skeletal muscle angiogenesis by angiotensin-(1-7) in Dahl salt-sensitive rats.
PloS one - 1 Jan 2020
Exner Eric C, Geurts Aron M, Hoffmann Brian R, Casati Marc, Stodola Timothy, Dsouza Nikita R, Zimmermann Michael, Lombard Julian H, Greene Andrew S
Abstract excerpt
The heptapeptide angiotensin-(1-7) (Ang-(1-7)) is protective in the cardiovascular system through its induction of vasodilator production and angiogenesis. Despite acting antagonistically to the effects of elevated, pathophysiological levels of angiotensin II (AngII), recent evidence has identified convergent and beneficial effects of low levels of both Ang-(1-7) and AngII. Previous work identified the AngII...
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