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Article

Interindividual Variability of Apixaban Plasma Concentrations: Influence of Clinical and Genetic Factors in a Real-Life Cohort of Atrial Fibrillation Patients.

Genes - 17 Apr 2020

Roşian Adela-Nicoleta, Roşian Ştefan Horia, Kiss Bela, Ştefan Maria Georgia, Trifa Adrian Pavel, Ober Camelia Diana, Anchidin Ovidiu, Buzoianu Anca Dana

Abstract excerpt

(1) Background: Prescribing apixaban for stroke prevention has significantly increased in patients with non-valvular atrial fibrillation (NVAF). The ABCB1 genotype can influence apixaban absorption and bioavailability. The aim of the present study was to assess the factors that influence apixaban's plasma level and to establish if a certain relationship has clinical relevance. (2) Methods: Fifty-three NVAF...

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Source

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Identifiers

PMID: 32316515
DOI: 10.3390/genes11040438
PMCID: PMC7230214

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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