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Article

MicroRNA-155 Deficiency Exacerbates Trypanosoma cruzi Infection.

Infection and immunity - 22 Jun 2020

Jha Bijay K, Varikuti Sanjay, Seidler Gabriella R, Volpedo Greta, Satoskar Abhay R, McGwire Bradford S

Abstract excerpt

Chagas disease, caused by the intracellular protozoan parasite Trypanosoma cruzi, is a public health problem affecting 6 to 8 million people, mainly in Latin America. The role of microRNAs in the pathogenesis of Chagas disease has not been well described. Here, we investigate the role of microRNA-155 (miR-155), a proinflammatory host innate immune regulator responsible for T helper type 1 and type 17 (Th1 and...

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Identifiers

PMID: 32312766
DOI: 10.1128/IAI.00948-19
PMCID: PMC7309613

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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