Article
MicroRNA-155 knockout mice are susceptible to Mycobacterium tuberculosis infection.
Tuberculosis (Edinburgh, Scotland) - 1 May 2015
Iwai Hiroki, Funatogawa Keiji, Matsumura Kazunori, Kato-Miyazawa Masako, Kirikae Fumiko, Kiga Kotaro, Sasakawa Chihiro, Miyoshi-Akiyama Tohru, Kirikae Teruo
Abstract excerpt
MicroRNAs (miRNAs) are short, conserved, non-coding RNA molecules that repress translation, followed by the decay of miRNA-targeted mRNAs that encode molecules involved in cell differentiation, development, immunity and apoptosis. At least six miRNAs, including microRNA-155 (miR-155), were up-regulated when born marrow-derived macrophages from C57BL/6 mice were infected with Mycobacterium tuberculosis Erdman....
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