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ScmR, a Global Regulator of Gene Expression, Quorum Sensing, pH Homeostasis, and Virulence in Burkholderia thailandensis

17 Apr 2020

Abstract excerpt

Coordination of the expression of genes associated with bacterial virulence and environmental adaptation is often dependent on quorum sensing (QS). The QS circuitry of the nonpathogenic bacterium Burkholderia thailandensis , widely used as a model system for the study of the human pathogen Burkholderia pseudomallei , is complex. We found that the LysR-type transcriptional regulator, ScmR, which is highly...

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PMID: 32312745
DOI: 10.1128/jb.00776-19

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