Article
Necrotic cell death induces melanotic mass formation in Drosophila.
Biochemical and biophysical research communications - 11 Jun 2020
Park JinYoung, Lee Ji-Hyun, Lee Youngbin, Lee Donghoon, Kim Moon Jong, Choe Kwang-Min
Abstract excerpt
The immune system protects its host from not only invading parasites and parasitoids, but also altered self tissue, including dying cells. Necrotic cells are strongly immunogenic, but in Drosophila this has not been directly addressed, due partially to the fact that knowledge about necrosis in Drosophila currently lags behind that for other models. Upon the loss of cell matrix attachment, endocycling polyploid...
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