Article

Tsc2 mutation rather than Tsc1 mutation dominantly causes a social deficit in a mouse model of tuberous sclerosis complex

2022-10-31

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> : Tuberous sclerosis complex (TSC) is an autosomal dominant disorder that is associated with neurological symptoms, including autism spectrum disorder. Tuberous sclerosis complex is caused by pathogenic germline mutations of either the <italic>TSC1</italic> or <italic>TSC2</italic> gene, but somatic mutations were identified in both genes, and the combined...

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Literature Corpus work: f8dbb262-c4fc-5863-a7e8-eaae3cd8e6b4
DOI: 10.21203/rs.3.rs-2074843/v2

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