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Article

Altered ultrasonic vocalizations in a tuberous sclerosis mouse model of autism

1 Jun 2010

Abstract excerpt

Tuberous sclerosis (TSC) is an autosomally dominant neurocutaneous disease notable for its high comorbidity with autism in human patients. Studies of murine models of tuberous sclerosis have found defects in cognition and learning, but thus far have not uncovered deficits in social behaviors relevant to autism. To explore social communication and interaction in TSC2 heterozygous mice, we recorded ultrasonic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 20534473
DOI: 10.1073/pnas.1005620107

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