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Article

The prevalence of HPA-1a alloimmunization and the potential risk of FNAIT depend on both the DRB3*01:01 allele and associated DR-DQ haplotypes.

Scandinavian journal of immunology - 1 Jul 2020

Ahlen Maria Therese, Heide Gøril, Husebekk Anne, Skogen Bjørn, Kjeldsen-Kragh Jens, Stuge Tor B

Abstract excerpt

Alloimmunization against human platelet antigen (HPA)-1a during pregnancy can cause foetal/neonatal alloimmune thrombocytopenia (FNAIT) and severe bleeding in the foetus or newborn and likely depends on several factors. HPA-1a alloimmunization is associated with DRB3*01:01, which is associated with several DR-DQ haplotypes. However, it is not known to what extent these haplotypes contribute to the prevalence of...

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PMID: 32299122
DOI: 10.1111/sji.12890

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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