RNA-loaded nanoparticles for the treatment of hematological cancers

Abstract excerpt

• NPs play a crucial role in RNA-based hematological tumor therapies. • RNA-NPs have the ability to modify genetic and epigenetic alterations or the tumor microenvironment. • In vivo CAR-T cell generation is achievable through RNA-loaded NPs. • Pediatric patients with blood cancers may experience benefits from RNA-loaded NPs. • NPs significantly improve the delivery and efficacy of RNA therapy in preclinical...

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