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Plasma levels of polychlorinated biphenyl, genetic polymorphisms, and the risk of advanced stage endometriosis.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 Jul 2020

Kim Miran, Kim Sung Hoon, Kim Hyun Jin, Whang Dong Hee, Yun Sung-Cheol, Lee Sa Ra, Chae Hee Dong, Kang Byung Moon

Abstract excerpt

Both environmental and genetic factors interact and play a critical role in the pathogenesis of endometriosis. We analyzed the plasma levels of 12 polychlorinated biphenyl (PCB) congeners with genetic polymorphisms of glutathione-S-transferase M1 (GSTM1), glutathione-S-transferase T1 (GSTT1), and aryl hydrocarbon receptor repressor (AhRR) codon 185. Total sum of the 12 congeners was significantly higher in the...

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PMID: 32295439
DOI: 10.1080/09513590.2020.1753183

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