Article
Polymorphisms of dioxin receptor complex components and detoxification-related genes jointly confer susceptibility to advanced-stage endometriosis in the taiwanese han population.
American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Feb 2012
Wu Cheng-Hsuan, Guo Chao-Yu, Yang Jyuer-Ger, Tsai Horng-Der, Chang Yu-Jun, Tsai Pei-Chien, Hsu Chao-Chin, Kuo Pao-Lin
Abstract excerpt
PROBLEM: To establish a multilocus model for studying the effect of dioxin receptor complex components and detoxification-related enzymes on advanced endometriosis. METHOD OF STUDY: Six single-nucleotide polymorphisms (SNPs) and two deletion polymorphisms from eight genes (CYP1A1, CYP1B1, GSTM1, GSTT1, GSTP1, AhR, ARNT, and AhRR) were genotyped. RESULTS: In the single SNP analysis, GSTM1 null type and AhRR...
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