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Glutathione transferase polymorphisms and risk of endometriosis associated with polychlorinated biphenyls exposure in Italian women: a gene-environment interaction.

Fertility and sterility - 1 May 2012

Vichi Susanna, Medda Emanuela, Ingelido Anna Maria, Ferro Annamaria, Resta Serena, Porpora Maria Grazia, Abballe Annalisa, Nisticò Lorenza, De Felip Elena, Gemma Simonetta, Testai Emanuela

Abstract excerpt

OBJECTIVE: To investigate the occurrence of a gene-environment interaction between glutathione transferase (GST) gene polymorphisms (GSTM1, GSTT1, GSTP1, and GSTA1) and serum polychlorinated biphenyls (PCBs) levels. This is suggested as possible risk factors for endometriosis, a multifactorial gynecological disease. DESIGN: Case-control study conducted from 2002 to 2005. SETTING: Policlinico Umberto I, "Sapienza"...

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Source

Identifiers

PMID: 22424617
DOI: 10.1016/j.fertnstert.2012.02.027

Genes

GSTP1
GSTM1
GSTA1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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