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Article

Stretching Induces Overexpression of RhoA and Rac1 GTPases in Breast Cancer Cells

5 Dec 2019

Abstract excerpt

Rho GTPases are well known for regulating cell morphology and intracellular interactions. They can either be oncogenic or tumor suppressors. However, these proteins are associated with the acquirement of malignant features by cancer cells. It has been reported that the overexpression of protein markers of Rho family members such as RhoA and Rac1 is linked with carcinogenesis and the progression of a variety of...

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PMID: 32293133
DOI: 10.1002/adbi.201900222

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