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A Well-Defined H9N2 Avian Influenza Virus Genotype with High Adaption in Mammals was Prevalent in Chinese Poultry Between 2016 to 2019.

Viruses - 11 Apr 2020

Chen Zhaokun, Huang Qinghua, Yang Shaohua, Su Shuai, Li Baoquan, Cui Ning, Xu Chuantian

Abstract excerpt

H9N2 subtype avian influenza virus (AIV) is widely prevalent in poultry, and the virus is becoming adaptive to mammals, which poses pandemic importance. Here, BALB/c mice were employed as a model to evaluate the adaption in mammals of 21 field H9N2 viruses isolated from avian species between 2016 to 2019 in China. The replication capacity of the viruses was evaluated in the lungs of mice. The pathogenicity of the...

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Identifiers

PMID: 32290398
DOI: 10.3390/v12040432
PMCID: PMC7232211

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