Article
Ethnicity-Dependent Effects of Schizophrenia Risk Variants of the OLIG2 Gene on OLIG2 Transcription and White Matter Integrity.
Schizophrenia bulletin - 1 Dec 2020
Komatsu Hiroshi, Takeuchi Hikaru, Kikuchi Yoshie, Ono Chiaki, Yu Zhiqian, Iizuka Kunio, Takano Yuji, Kakuto Yoshihisa, Funakoshi Shunichi, Ono Takashi, Ito Junko, Kunii Yasuto, Hino Mizuki, Nagaoka Atsuko, Iwasaki Yasushi, Yamamori Hidenaga, Yasuda Yuka, Fujimoto Michiko, Azechi Hirotsugu, Kudo Noriko, Hashimoto Ryota, Yabe Hirooki, Yoshida Mari, Saito Yuko, Kakita Akiyoshi, Fuse Nobuo, Kawashima Ryuta, Taki Yasuyuki, Tomita Hiroaki
Abstract excerpt
Previous studies have indicated associations between several OLIG2 gene single-nucleotide polymorphisms (SNPs) and susceptibility to schizophrenia among Caucasians. Consistent with these findings, postmortem brain and diffusion tensor imaging studies have indicated that the schizophrenia-risk-associated allele (A) in the OLIG2 SNP rs1059004 predicts lower OLIG2 gene expression in the dorsolateral prefrontal...
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