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Article

Evidence that variation in the oligodendrocyte lineage transcription factor 2 (OLIG2) gene is associated with psychosis in Alzheimer's disease.

Neuroscience letters - 11 Sept 2009

Sims R, Hollingworth P, Moskvina V, Dowzell K, O'Donovan M C, Powell J, Lovestone S, Brayne C, Rubinsztein D, Owen M J, Williams J, Abraham R

Abstract excerpt

Psychotic symptoms are common in individuals with Alzheimer's disease (AD), and define a phenotype associated with more rapid cognitive and functional decline. Evidence suggests that psychotic symptoms may be influenced by genetic factors, and recent studies in schizophrenia, bipolar affective disorder (BPAD) and Alzheimer's disease with psychosis (AD+P) suggest that psychosis susceptibility or modifier genes may...

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Identifiers

PMID: 19477230
DOI: 10.1016/j.neulet.2009.05.051

Genes

OLIG2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Evidence that variation in the oligodendrocyte lineage transcription factor 2 (OLIG2) gene is associated with psychosis in Alzheimer's disease.PMID 19477230Read ↗

Convergent evidence that oligodendrocyte lineage transcription factor 2 (OLIG2) and interacting genes influence susceptibility to schizophrenia.Semantic proximity Read ↗

Ethnicity-Dependent Effects of Schizophrenia Risk Variants of the OLIG2 Gene on OLIG2 Transcription and White Matter Integrity.Semantic proximity Read ↗

ASSOCIATION STUDY BETWEEN OLIGODENDROCYTE TRANSCRIPTION FACTOR 2 GENE AND OBSESSIVE-COMPULSIVE DISORDER IN A CHINESE HAN POPULATION.Semantic proximity Read ↗

Positive association between OLIG2 and schizophrenia in the Chinese Han population.Semantic proximity Read ↗

Risk variant of oligodendrocyte lineage transcription factor 2 is associated with reduced white matter integrity.Semantic proximity Read ↗

A genetic family-based association study of OLIG2 in obsessive-compulsive disorder.Semantic proximity Read ↗

Expression of oligodendrocyte-associated genes in dorsolateral prefrontal cortex of patients with schizophrenia.Semantic proximity Read ↗

Genome-wide association study of Alzheimer's disease with psychotic symptoms.Semantic proximity Read ↗

Investigation of OLIG2 as a candidate gene for schizophrenia and autism spectrum disorder.Semantic proximity Read ↗

Oligodendroglial abnormalities in schizophrenia, mood disorders and substance abuse. Comorbidity, shared traits, or molecular phenocopies?Semantic proximity Read ↗

Dysregulation of myelination-related genes in schizophrenia.Semantic proximity Read ↗

The 2',3'-cyclic nucleotide 3'-phosphodiesterase and oligodendrocyte lineage transcription factor 2 genes do not appear to be associated with schizophrenia in the Japanese population.Semantic proximity Read ↗

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