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Article

Genetically engineered control of phenotypic structure in microbial colonies.

Nature microbiology - 1 May 2020

Bittihn Philip, Didovyk Andriy, Tsimring Lev S, Hasty Jeff

Abstract excerpt

Rapid advances in cellular engineering1,2 have positioned synthetic biology to address therapeutic3,4 and industrial5 problems, but a substantial obstacle is the myriad of unanticipated cellular responses in heterogeneous real-world environments such as the gut6,7, solid tumours8,9, bioreactors10 or soil11. Complex interactions between the environment and cells often arise through non-uniform nutrient...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32284568
DOI: 10.1038/s41564-020-0686-0
PMCID: PMC8172263

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