Article
Evaluation of the association between five genetic variants and primary open-angle glaucoma in a Han Chinese population.
Ophthalmic genetics - 1 Jun 2020
Li Kecheng, Yang Chen, Wan Xiaoqin, Xu Jiaxin, Luo Qian, Cheng Yilian, Peng Jie, Gong Bo, Jiang Li, Liu Yuping, Shuai Ping
Abstract excerpt
PURPOSE: A large genome-wide association study showed that five new variants, {EPDR1 (rs3816415), CHAT (rs1258267), GLIS3 (rs736893), FERMT2 (rs7494379), and DPM2-FAM102A (rs3739821)}, were associated primary angle-closure glaucoma (PACG). Considering the shared clinical features between primary open-angle glaucoma (POAG) and PACG, this study was conducted to investigate the association of these genetic variants...