Article
Evaluation of Primary Angle-Closure Glaucoma Susceptibility Loci for Estimating Angle Closure Disease Severity.
Ophthalmology - 1 Mar 2021
Liu Chang, Nongpiur Monisha E, Cheng Ching-Yu, Khor Chiea-Chuen, Yu Marco, Husain Rahat, Ho Ching Lin, Wong Tina T, Boey Pui Yi, Perera Shamira, Wong Tien Yin, Vithana Eranga N, Aung Tin
Abstract excerpt
PURPOSE: To investigate whether recently identified genetic loci for primary angle-closure glaucoma (PACG) are associated with disease severity. DESIGN: Case-control study. PARTICIPANTS: Eight hundred four PACG patients and 943 control participants of Chinese ethnicity from Singapore. METHODS: The 8 PACG-associated single nucleotide polymorphisms (SNPs; rs11024102 at PLEKHA7, rs3753841 at COL11A1, rs1015213...
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