Article
Heme oxygenase-1 promoter (GT) n polymorphism associates with HIV neurocognitive impairment.
Neurology(R) neuroimmunology & neuroinflammation - 1 May 2020
Garza Rolando, Gill Alexander J, Bastien Brandon L, Garcia-Mesa Yoelvis, Gruenewald Analise L, Gelman Benjamin B, Tsima Billy, Gross Robert, Letendre Scott L, Kolson Dennis L
Abstract excerpt
OBJECTIVE: To determine whether regulatory variations in the heme oxygenase-1 (HO-1) promoter (GT) n dinucleotide repeat length could identify unique population genetic risks for neurocognitive impairment (NCI) in persons living with HIV (PLWH), we genotyped 528 neurocognitively assessed PLWH of European American and African American descent and linked genotypes to cognitive status. METHODS: In this...
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