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Article

An LCM-based genomic analysis of SPEM, Gastric Cancer and Pyloric Gland Adenoma in an Asian cohort.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Oct 2020

Srivastava Supriya, Huang Kie Kyon, Rebbani Khadija, Das Kakoli, Fazreen Zul, Yeoh Khay Guan, Tan Patrick, Teh Ming

Abstract excerpt

Spasmolytic polypeptide-expressing metaplasia (SPEM) and pyloric gland adenoma (PGA) in the stomach are metaplastic and neoplastic lesions, respectively, in which gastric body glands are replaced by pyloric glands. The aim of this study was to evaluate the genomic profile of SPEM and compare it with intestinal-type gastric cancer (GC) and PGA. Thirteen gastrectomies showing PGA with or without dysplasia, GC and...

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PMID: 32269290
DOI: 10.1038/s41379-020-0520-5

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