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Article

Next-generation sequencing identifies 2 genomically distinct groups among pyloric gland adenomas.

Human pathology - 1 Mar 2020

Setia Namrata, Wanjari Pankhuri, Yassan Lindsay, Niu Nifang, Kadri Sabah, Ritterhouse Lauren, Misdraji Joseph, Brown Ian, Segal Jeremy, Hart John

Abstract excerpt

The molecular alterations identified among pyloric gland adenomas (PGAs) in the published literature are based on polymerase chain reaction of targeted genes, and next-generation sequencing (NGS) has not been performed. In this study, we performed NGS and correlated the molecular alterations with the histologic grade of dysplasia and immunohistochemical findings in a cohort of PGAs. Successful DNA extraction and...

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Identifiers

PMID: 31783043
DOI: 10.1016/j.humpath.2019.11.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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