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Article

Molecular Dynamics Simulation and Kinetic Study of Fluoride Binding to V21C/V66C Myoglobin with a Cytoglobin-like Disulfide Bond.

International journal of molecular sciences - 4 Apr 2020

Yin Lu-Lu, Xu Jia-Kun, Wang Xiao-Juan, Gao Shu-Qin, Lin Ying-Wu

Abstract excerpt

Protein design is able to create artificial proteins with advanced functions, and computer simulation plays a key role in guiding the rational design. In the absence of structural evidence for cytoglobin (Cgb) with an intramolecular disulfide bond, we recently designed a de novo disulfide bond in myoglobin (Mb) based on structural alignment (i.e., V21C/V66C Mb double mutant). To provide deep insight into the...

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Identifiers

PMID: 32260401
DOI: 10.3390/ijms21072512
PMCID: PMC7177771

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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