Dynamic features of carboxy cytoglobin distal mutants investigated by molecular dynamics simulations.

doi:10.1007/s00775-016-1334-2

Article

Dynamic features of carboxy cytoglobin distal mutants investigated by molecular dynamics simulations.

Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry - 1 Apr 2016

Zhao Cong, Du Weihong

Abstract excerpt

Cytoglobin (Cgb) is a member of hemoprotein family with roles in NO metabolism, fibrosis, and tumourigenesis. Similar to other hemoproteins, Cgb structure and functions are markedly influenced by distal key residues. The sixth ligand His(81) (E7) is crucial to exogenous ligand binding, heme pocke...

Topics

Cytoglobin
Globins
Molecular Dynamics Simulation
Mutation

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.