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Article

Transgenerational Inheritance of Reproductive and Metabolic Phenotypes in PCOS Rats.

Frontiers in endocrinology - 1 Jan 2020

Zhang Hao-Lin, Yi Ming, Li Dong, Li Rong, Zhao Yue, Qiao Jie

Abstract excerpt

Androgen exposure of female fetuses could be an important factor in the development of polycystic ovary syndrome (PCOS) in subsequent generations. The present study aimed to investigate the transgenerational effects of PCOS on the growth, reproduction, and metabolism of the first- and second-generation offspring in rats. Female F0 rats received excessive dehydroepiandrosterone (DHEA) exposure to establish PCOS or...

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Source

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Identifiers

PMID: 32256454
DOI: 10.3389/fendo.2020.00144
PMCID: PMC7093372

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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