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Article

Epigenetic inheritance of PCOS by developmental programming and germline transmission

27 Dec 2024

Abstract excerpt

Polycystic ovary syndrome (PCOS) is a prevalent endocrine and metabolic disorder, affecting approximately 11-13% of women of reproductive age. Women with PCOS experience a higher prevalence of infertility, pregnancy complications, and cardiometabolic disorders such as obesity, insulin resistance, and type 2 diabetes mellitus. Furthermore, psychiatric comorbidities, including depression and anxiety, significantly...

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PMID: 39732517
DOI: 10.1016/j.tem.2024.12.002

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