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Article

Cell and molecular transitions during efficient dedifferentiation.

eLife - 7 Apr 2020

Nichols John Me, Antolović Vlatka, Reich Jacob D, Brameyer Sophie, Paschke Peggy, Chubb Jonathan R

Abstract excerpt

Dedifferentiation is a critical response to tissue damage, yet is not well understood, even at a basic phenomenological level. Developing Dictyostelium cells undergo highly efficient dedifferentiation, completed by most cells within 24 hr. We use this rapid response to investigate the control features of dedifferentiation, combining single cell imaging with high temporal resolution transcriptomics. Gene...

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Identifiers

PMID: 32255425
DOI: 10.7554/eLife.55435
PMCID: PMC7190356

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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