Article
Linkage disequilibrium and haplotype analysis of Src and Yes1 genes in thyroid cancer.
Future oncology (London, England) - 1 Apr 2020
Nisar Asif, Mahjabeen Ishrat, Mehmood Azhar, Ahmed Malik Waqar, Khurshid Khalida, Kayani Mahmood Akhtar
Abstract excerpt
Purpose: This study was planned to examine the effects of Src and Yes1 single nucleotide polymorphism (SNPs) on the risk of thyroid cancer in 499 patients and 500 controls. Materials & methods: Three SNPs of Src gene and three SNPs of Yes1 gene were analyzed using Tetra-primer ARMS-PCR followed by sequencing. Results: rs121913314 of Src gene genotype TT showed 32-fold increased risk of thyroid cancer and...
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