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Article

Biological functions of the autophagy-related proteins Atg4 and Atg8 in Cryptococcus neoformans.

PloS one - 1 Jan 2020

Roberto Thiago Nunes, Lima Ricardo Ferreira, Pascon Renata Castiglioni, Idnurm Alexander, Vallim Marcelo Afonso

Abstract excerpt

Autophagy is a mechanism responsible for intracellular degradation and recycling of macromolecules and organelles, essential for cell survival in adverse conditions. More than 40 autophagy-related (ATG) genes have been identified and characterized in fungi, among them ATG4 and ATG8. ATG4 encodes a cysteine protease (Atg4) that plays an important role in autophagy by initially processing Atg8 at its C-terminus...

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Identifiers

PMID: 32251488
DOI: 10.1371/journal.pone.0230981
PMCID: PMC7135279

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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