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Article

The crucial role of the regulatory mechanism of the Atg1/ULK1 complex in fungi

26 Oct 2022

Abstract excerpt

Autophagy, an evolutionarily conserved cellular degradation pathway in eukaryotes, is hierarchically regulated by autophagy-related genes (Atgs). The Atg1/ULK1 complex is the most upstream factor involved in autophagy initiation. Here，we summarize the recent studies on the structure and molecular mechanism of the Atg1/ULK1 complex in autophagy initiation, with a special focus on upstream regulation and downstream...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 36386635
DOI: 10.3389/fmicb.2022.1019543

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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