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Article

ATG Genes Influence the Virulence of Cryptococcus neoformans through Contributions beyond Core Autophagy Functions

9 Jul 2018

Abstract excerpt

The process of autophagy is conserved among all eukaryotes from yeast to humans and is mainly responsible for bulk degradation of cellular contents and nutrient recycling during starvation. Autophagy has been suggested to play a role in the pathogenesis of the opportunistic human fungal pathogen Cryptococcus neoformans , potentially through a contribution to the export of virulence factors.

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PMID: 29986893
DOI: 10.1128/iai.00069-18

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